Resistant Superbugs: Race against Time

Nanoantibiotics: strategic assets in the fight against drug-resistant superbugs

Antimicrobial characteristics of metals reveal that Ag despite its economic constraints remains the most popular antibiotic agent. Antimicrobial characteristics of copper nanoparticles (CNPs) are not well understood. To our knowledge, no systematic comparative study on microbial properties of silver nanoparticles (SNPs) and CNPs exists. In this article, a comparative study on microbial properti...

The race against time

Breaking the Spell: Combating Multidrug Resistant ‘Superbugs’

Multidrug-resistant (MDR) bacteria have become a severe threat to community wellbeing. Conventional antibiotics are getting progressively more ineffective as a consequence of resistance, making it imperative to realize improved antimicrobial options. In this review we emphasized the microorganisms primarily reported of being resistance, referred as ESKAPE pathogens (Enterococcus faecium, Staphy...

Structure based virtual screening of novel inhibitors against multidrug resistant superbugs

Pathogenic microorganisms are persistently expressing resistance towards present generation antibiotics and are on the verge of joining the superbug family. Recent studies revealed that, notorious pathogens such as Salmonella typhi, Shigella dysenteriae and Vibrio cholerae have acquired multiple drug resistance and the treatment became a serious concern. This necessitates an alternative therape...

Essential Oils and Future Antibiotics: New Weapons against Emerging ‘Superbugs’?

Antibiotic resistance is emerging at an alarming rate, outpacing current research and development efforts to combat this trend. As a result, many infectious diseases have become difficult to treat; in some cases, no treatment options exist. The search for new antibiotics must accelerate to avoid returning to the ‘pre-antibiotic’ era. Ancient remedies, including essential oils and their componen...